Chemical Immunology Lab

VAN KLAVEREN, Sjors, HASSAN, Mujtaba, HÅKANSSON, Maria, JOHNSSON, Richard E., LARSSON, Jessica, JAKOPIN, Žiga, ANDERLUH, Marko, LEFFLER, Hakon, TOMAŠIČ, Tihomir, NILSSON, Ulf. Galectin-8N-selective 4-halophenylphthalazinone-galactals double π stack in a unique pocket. ACS Medicinal Chemistry Letters. 2024, vol. 15, iss. 8, str. 1319-1324. https://pubs.acs.org/doi/10.1021/acsmedchemlett.4c00212, DOI: 10.1021/acsmedchemlett.4c00212.

JANEŽ, Špela, GUZELJ, Samo, JAKOPIN, Žiga. Linker chemistry and connectivity fine-tune the immune response and kinetic solubility of conjugated NOD2/TLR7 agonists. Bioconjugate chemistry. 2024, vol. 35, no. 11, str. 1723-1731, https://pubs.acs.org/doi/10.1021/acs.bioconjchem.4c00321.

WEISS, Veronika, GOBEC, Martina, JAKOPIN, Žiga. Halogenation of common phenolic household and personal care product ingredients enhances their AhR-modulating capacity. Chemosphere. 2024, vol. 350, [art. no. 141116], 9 str.. https://www.sciencedirect.com/science/article/pii/S0045653524000092.

PELETTA, Allegra, MARMY, Aurélie, GUZELJ, Samo, RAMOS BARROS, Alcidia, JAKOPIN, Žiga, BORCHARD, Gerrit. Preliminary results on novel adjuvant combinations suggest enhanced immunogenicity of whole inactivated pandemic influenza vaccines. Frontiers in drug delivery. 2024, vol. 4, 14 str., https://www.frontiersin.org/journals/drug-delivery/articles/10.3389/fddev.2024.1382266/full.

RUSSO, Camilla, RUSSOMANNO, Pasquale, D’AMORE, Vincenzo Maria, ALFANO, Antonella Ilenia, SANTORO, Federica, GUZELJ, Samo, GOBEC, Martina, AMATO, Jussara, PAGANO, Bruno, JAKOPIN, Žiga, et al. Discovery of 2,3-diaminoindole derivatives as a novel class of NOD antagonists. Journal of medicinal chemistry. 2024, vol. 67, iss. 4, str. 3004-3017, https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c02094, DOI: 10.1021/acs.jmedchem.3c02094.

JANEŽ, Špela, GUZELJ, Samo, KOCBEK, Petra, DE VLIEGER, Eveline A., SLÜTTER, Bram, JAKOPIN, Žiga. Distinctive immune signatures driven by structural alterations in desmuramylpeptide NOD2 agonists. Journal of medicinal chemistry. 2024, vol. 67, iss. 19, str. 17585-17607, https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01577.

NOWAK, Karolina, JAKOPIN, Žiga. In silico profiling of endocrine-disrupting potential of bisphenol analogues and their halogenated transformation products. Food and chemical toxicology. 2023, vol. , art.113623, <v tisku>, ilustr. ISSN 1873-6351. https://www.sciencedirect.com/science/article/pii/S027869152300025X?via%3Dihub#undfig1, DOI: 10.1016/j.fct.2023.113623. [COBISS.SI-ID 138155779]

WEISS, Veronika, GOBEC, Martina, JAKOPIN, Žiga. In vitro investigation of immunomodulatory activities of selected UV-filters. Food and chemical toxicology. 2023, vol. , <v tisku>, ilustr., graf. prikazi. ISSN 0278-6915. https://www.sciencedirect.com/science/article/pii/S0278691523000868, DOI: 10.1016/j.fct.2023.113684. [COBISS.SI-ID 142404867]

GUZELJ, Samo, WEISS, Matjaž, SLÜTTER, Bram, FRKANEC, Ruža, JAKOPIN, Žiga. Covalently conjugated NOD2/TLR7 agonists are potent and versatile immune potentiators. Journal of medicinal chemistry. [Online ed.]. 2022, vol. 65, no. 22, str. 15085–15101, ilustr. ISSN 1520-4804. https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.2c00808#, DOI: 10.1021/acs.jmedchem.2c00808. [COBISS.SI-ID 128189187]

GUZELJ, Samo, BIZJAK, Špela, JAKOPIN, Žiga. Discovery of desmuramylpeptide NOD2 agonists with single-digit nanomolar potency. ACS Medicinal Chemistry Letters. 2022, vol. 13, iss. 8, str. 1270-1277, ilustr. ISSN 1948-5875. https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.2c00121, DOI: 10.1021/acsmedchemlett.2c00121. [COBISS.SI-ID 117643267]

KLANČIČ, Veronika, GOBEC, Martina, JAKOPIN, Žiga. Environmental contamination status with common ingredients of household and personal care products exhibiting endocrine-disrupting potential. Environmental science and pollution research. 2022, vol. 29, str. 73648–73674, tabele. ISSN 1614-7499. https://link.springer.com/article/10.1007/s11356-022-22895-z, DOI: 10.1007/s11356-022-22895-z. [COBISS.SI-ID 122859523]

KLANČIČ, Veronika, GOBEC, Martina, JAKOPIN, Žiga. Halogenated ingredients of household and personal care products as emerging endocrine disruptors. Chemosphere. [Print ed.]. 2022, vol. 303, part 1, art. 134824, 19 str., ilustr. ISSN 0045-6535. https://www.sciencedirect.com/science/article/pii/S0045653522013170?via%3Dihub, DOI: 10.1016/j.chemosphere.2022.134824. [COBISS.SI-ID 117775107]

GUZELJ, Samo, ŠIŠIĆ, Marcela, BIZJAK, Špela, FRKANEC, Leo, FRKANEC, Ruža, JAKOPIN, Žiga. Lipidation of NOD2 agonists with adamantane and stearoyl moieties differentially regulates their In vivo adjuvant activity. Pharmaceutics. [Online ed.]. 2022, vol. 14, iss. 12, art. 2755, 9 str., ilustr. ISSN 1999-4923. https://www.mdpi.com/1999-4923/14/12/2755, DOI: 10.3390/pharmaceutics14122755. [COBISS.SI-ID 133033219]

GUZELJ, Samo, TOMAŠIČ, Tihomir, JAKOPIN, Žiga. Novel scaffolds for modulation of NOD2 identified by pharmacophore-based virtual screening. Biomolecules. 2022, vol. 12, iss. 8, art. 1054, 17 str., ilustr. ISSN 2218-273X. https://www.mdpi.com/2218-273X/12/8/1054, DOI: 10.3390/biom12081054. [COBISS.SI-ID 117616387]

GUZELJ, Samo, JAKOPIN, Žiga. Nucleotide-Binding oligomerization domain 1/Toll-like receptor 4 co-engagement promotes non-specific immune response against K562 cancer cells. Frontiers in pharmacology. 2022, vol. 13, art. 920928, 12 str., ilustr. ISSN 1663-9812. https://www.frontiersin.org/articles/10.3389/fphar.2022.920928/full, DOI: 10.3389/fphar.2022.920928. [COBISS.SI-ID 117623555]

JAKOPIN, Žiga. Assessment of the endocrine-disrupting potential of halogenated parabens : an in silico approach. Chemosphere. [Print ed.]. 2021, vol. 264, part 1, str. 1-11, tabele. ISSN 0045-6535. https://www.sciencedirect.com/science/article/pii/S0045653520326424, DOI: 10.1016/j.chemosphere.2020.128447. [COBISS.SI-ID 30194691]

HASSAN, Mujtaba, VAN KLAVEREN, Sjors, HÅKANSSON, Maria, DIEHL, Carl, KOVAČIČ, Rebeka, BAUSSIÈRE, Floriane, SUNDIN, Anders, DERNOVŠEK, Jaka, ANDERLUH, Marko, TOMAŠIČ, Tihomir, JAKOPIN, Žiga, et al. Benzimidazole-galactosides bind selectively to the galectin-8 N-terminal domain : structure-based design and optimisation. European journal of medicinal chemistry. [Print ed.]. 2021, vol. 223, str. 1-13, ilustr. ISSN 0223-5234. https://www.sciencedirect.com/science/article/pii/S0223523421005134?via%3Dihub, DOI: 10.1016/j.ejmech.2021.113664. [COBISS.SI-ID 68254211]

NABERGOJ, Sanja, MARKOVIČ, Tijana, AVSEC, Damjan, GOBEC, Martina, PODGORNIK, Helena, JAKOPIN, Žiga, MLINARIČ-RAŠČAN, Irena. EP4 receptor agonist L-902688 augments cytotoxic activities of ibrutinib, idelalisib, and venetoclax against chronic lymphocytic leukemia cells. Biochemical pharmacology. [Print ed.]. 2021, vol. 183, str. 1-14, ilustr. ISSN 0006-2952. https://www.sciencedirect.com/science/article/pii/S0006295220305888#!, DOI: 10.1016/j.bcp.2020.114352. [COBISS.SI-ID 43415299]

PAN, Guanxing, CHANG, Lin, ZHANG, Jianjun, LIU, Yangyang, DAHAN, Inbal, HU, Liang, ZHANG, Si, ZHANG, Jian, QIAO, Jianlin, JAKOPIN, Žiga, HU, Hu, et al. GSK669, a NOD2 receptor antagonist, inhibits thrombosis and oxidative stress via targeting platelet GPVI. Biochemical pharmacology. [Print ed.]. 2021, vol. 183, str. 1-12, ilustr. ISSN 0006-2952. https://www.sciencedirect.com/science/article/pii/S0006295220305517, DOI: 10.1016/j.bcp.2020.114315. [COBISS.SI-ID 36472835]

FRKANEC, Ruža, ŠTIMAC, Anton, JAKOPIN, Žiga, GUZELJ, Samo, GAZDEK, N., FRKANEC, Leo. Mixed adjuvant formulation based on peptide hydrogel and desmuramyl peptides: preparation and influence on specific immune reaction : 45th FEBS Congress, Molecules of Life: Towards New Horizons, Ljubljana, Slovenia, July 3-8, 2021. FEBS open bio. 2021, vol. 11, issue s1, str. 296. ISSN 2211-5463. https://febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13205, DOI: 10.1002/2211-5463.13205. [COBISS.SI-ID 69801475]

SCHIJNS, Virgil E. J. C., MAJHEN, Dragomira, VAN DER LEY, Peter, THAKUR, Aneesh, SUMMERFIELD, Artur, BERISIO, Rita, NATIVI, Cristina, FERNÁNDEZ-TEJADA, Alberto, ÁLVEREZ-DOMINGUEZ, Carmen, JAKOPIN, Žiga, et al. Rational vaccine design in times of emerging diseases : the critical choices of immunological correlates of protection, vaccine antigen and immunomodulation. Pharmaceutics. [Online ed.]. 2021, vol. 13, iss. 4, str. 1-30, ilustr. ISSN 1999-4923. https://www.mdpi.com/1999-4923/13/4/501, DOI: 10.3390/pharmaceutics13040501. [COBISS.SI-ID 58558723]

GUZELJ, Samo, NABERGOJ, Sanja, GOBEC, Martina, PAJK, Stane, KLANČIČ, Veronika, SLÜTTER, Bram, FRKANEC, Ruža, ŠTIMAC, Adela, ŠKET, Primož, PLAVEC, Janez, MLINARIČ-RAŠČAN, Irena, JAKOPIN, Žiga. Structural fine-tuning of desmuramylpeptide NOD2 agonists defines their in vivo adjuvant activity. Journal of medicinal chemistry. 2021, vol. 64, iss. 11, str. 7809-7838, ilustr. ISSN 0022-2623. https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00644, DOI: 10.1021/acs.jmedchem.1c00644. [COBISS.SI-ID 64930051]

HASSAN, Mujtaba, BAUSSIÈRE, Floriane, GUZELJ, Samo, SUNDIN, Anders, HÅKANSSON, Maria, KOVAČIČ, Rebeka, LEFFLER, Hakon, TOMAŠIČ, Tihomir, ANDERLUH, Marko, JAKOPIN, Žiga, et al. Structure-guided design of D-galactal derivatives with high affinity and selectivity for the galectin-8 n-terminal domain. ACS Medicinal Chemistry Letters. 2021, vol. 12, iss. 11, str. 1745-1752, ilustr. ISSN 1948-5875. https://pubs.acs.org/doi/full/10.1021/acsmedchemlett.1c00371, DOI: 10.1021/acsmedchemlett.1c00371. [COBISS.SI-ID 83202819]

JAKOPIN, Žiga. 2-aminothiazoles in drug discovery : privileged structures or toxicophores?. Chemico-biological interactions. [Print ed.]. 2020, vol. 330, str. 1-8, ilustr. ISSN 0009-2797. https://www.sciencedirect.com/science/article/pii/S000927972030987X, DOI: 10.1016/j.cbi.2020.109244. [COBISS.SI-ID 26594819]

SCHIJNS, Virgil E. J. C., FERNÁNDEZ-TEJADA, Alberto, BARJAKTAROVIĆ, Žarko, BOUZALAS, Ilias, BRIMNES, Jens, CHERNYSH, Sergey, GIZURARSON, Sveinbjorn, GURSEL, Ihsan, JAKOPIN, Žiga, LAWRENZ, Maria, et al. Modulation of immune responses using adjuvants to facilitate therapeutic vaccination. Immunological reviews. 2020, vol. 296, iss. 1, str. 169-190, ilustr. ISSN 1600-065X. https://onlinelibrary.wiley.com/doi/full/10.1111/imr.12889, DOI: 10.1111/imr.12889. [COBISS.SI-ID 20856067]

GUZELJ, Samo, GOBEC, Martina, URBANČIČ, Dunja, MLINARIČ-RAŠČAN, Irena, CORSINI, Emanuela, JAKOPIN, Žiga. Structural features and functional activities of benzimidazoles as NOD2 antagonists. European journal of medicinal chemistry. [Print ed.]. Mar. 2020, vol. 190, str. 1-15, ilustr. ISSN 0223-5234. https://www.sciencedirect.com/science/article/pii/S0223523420300568?via%3Dihub, https://www.sciencedirect.com/science/article/pii/S0223523420300568?via%3Dihub#appsec1, DOI: 10.1016/j.ejmech.2020.112089. [COBISS.SI-ID 4874097]

GUZELJ, Samo, JAKOPIN, Žiga. Synthesis of conformationally constrained d-Glu-meso-DAP analogs as innate immune agonists. Molecules. 2020, vol. 25, no. 22, str. 1-13, ilustr. ISSN 1420-3049. https://www.mdpi.com/1420-3049/25/22/5228, DOI: 10.3390/molecules25225228. [COBISS.SI-ID 36482307]

NABERGOJ, Sanja, MLINARIČ-RAŠČAN, Irena, JAKOPIN, Žiga. Harnessing the untapped potential of NOD ligands for cancer immunotherapy. Medicinal research reviews. 2019, vol. 39, iss. 5, str. 1447-1484, ilustr. ISSN 1098-1128. https://onlinelibrary.wiley.com/doi/full/10.1002/med.21557, DOI: 10.1002/med.21557. [COBISS.SI-ID 4641905]

MRAVLJAK, Janez, JAKOPIN, Žiga. Iron-binding and anti-fenton properties of novel amino acid-derived cyclic imide dioximes. Antioxidants. 2019, vol. 8, iss. 10, str. 1-12, ilustr. ISSN 2076-3921. https://www.mdpi.com/2076-3921/8/10/473/htm, DOI: 10.3390/antiox8100473. [COBISS.SI-ID 4819569]

JAKOPIN, Žiga. Risks associated with fat burners : a toxicological perspective. Food and chemical toxicology. Jan. 2019, vol. 123, str. 205-224, ilustr. ISSN 0278-6915. https://www.sciencedirect.com/science/article/pii/S0278691518307907?via%3Dihub, DOI: 10.1016/j.fct.2018.10.051. [COBISS.SI-ID 4624753]

JAKOPIN, Žiga, CORSINI, Emanuela. THP-1 Cells and pro-inflammatory cytokine production : an in vitro tool for functional characterization of NOD1/NOD2 antagonists. International journal of molecular sciences. 2019, vol. 20, no. 17, str. 1-11, graf. prikazi. ISSN 1422-0067. https://www.mdpi.com/1422-0067/20/17/4265, DOI: 10.3390/ijms20174265. [COBISS.SI-ID 4770417]

GOBEC, Martina, TOMAŠIČ, Tihomir, ŠTIMAC, Adela, FRKANEC, Ruža, TRONTELJ, Jurij, ANDERLUH, Marko, MLINARIČ-RAŠČAN, Irena, JAKOPIN, Žiga. Discovery of nanomolar desmuramylpeptide agonists of the innate immune receptor nucleotide-binding oligomerization domain-containing protein 2 (NOD2) possessing immunostimulatory properties. Journal of medicinal chemistry. 2018, vol. 61, iss. 7, str. 2707-2724, ilustr. ISSN 0022-2623. https://pubs.acs.org/doi/10.1021/acs.jmedchem.7b01052, DOI: 10.1021/acs.jmedchem.7b01052. [COBISS.SI-ID 4483697]

JAKOPIN, Žiga. Ethyl 5-trichloromethyl-1,2,4-oxadiazole-3-carboxylate as a versatile building block in medicinal chemistry. Tetrahedron letters. [Print ed.]. Dec. 2018, vol. 59, iss. 49, str. 4320-4322, ilustr. ISSN 0040-4039. https://www.sciencedirect.com/science/article/pii/S0040403918312875?via%3Dihub, DOI: 10.1016/j.tetlet.2018.10.054. [COBISS.SI-ID 4625009]

PISANU, Maria Elena, MAUGERI-SACCÀ, Marcello, FATTORE, Luigi, BRUSCHINI, Sara, VITIS DE, Claudia, TABBÌ, Eugenio, BELLEI, Barbara, MIGLIANO, Emilia, KOVACS, Daniela, CAMERA, Emanuela, PICARDO, Mauro, JAKOPIN, Žiga, et al. Inhibition of stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma. Journal of experimental & clinical cancer research. 2018, vol. 37, str. 1-17, graf. prikazi. ISSN 1756-9966. https://jeccr.biomedcentral.com/articles/10.1186/s13046-018-0989-7, https://jeccr.biomedcentral.com/track/pdf/10.1186/s13046-018-0989-7, DOI: 10.1186/s13046-018-0989-7. [COBISS.SI-ID 4650353]

VALENCIC, Erica, ŠMID, Alenka, JAKOPIN, Žiga, TOMMASINI, Alberto, MLINARIČ-RAŠČAN, Irena. Repositioning drugs for rare immune diseases : hopes and challenges for a precision medicine. Current medicinal chemistry. 2018, vol. 25, iss. 24, str. 2764-2782, ilustr. ISSN 0929-8673. http://www.eurekaselect.com/155296/article, DOI: 10.2174/0929867324666170830101215. [COBISS.SI-ID 4371057]

PISANU, Maria Elena, NOTO, Alessia, VITIS, Claudia De, MORRONE, Stefania, SCOGNAMIGLIO, Giosuè, BOTTI, Gerardo, VENUTA, Federico, DISO, Daniele, JAKOPIN, Žiga, PADULA, Fabrizio, RICCI, Alberto, MARIOTTA, Salvatore, GIOVAGNOLI, Maria Rosaria, GIARNIERI, Enrico, AMELIO, Ivano, AGOSTINI, Massimiliano, MELINO, Gerry, CILIBERTO, Gennaro, MANCINI, Rita. Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells. Cancer letters. [Print ed.]. Oct. 2017, vol. 406, str. 93-104, graf. prikazi. ISSN 0304-3835. http://www.sciencedirect.com/science/article/pii/S0304383517304639?via%3Dihub, DOI: 10.1016/j.canlet.2017.07.027. [COBISS.SI-ID 4364401]

JAKOPIN, Žiga, ILAŠ, Janez, BARANČOKOVA, Michaela, BRVAR, Matjaž, TAMMELA, Päivi, SOLLNER DOLENC, Marija, TOMAŠIČ, Tihomir, KIKELJ, Danijel. Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors. European journal of medicinal chemistry. [Print ed.]. Apr. 2017, vol. 130, str. 171-184, ilustr. ISSN 0223-5234. http://ac.els-cdn.com/S0223523417301198/1-s2.0-S0223523417301198-main.pdf?_tid=814fa43e-024d-11e7-aa6e-00000aacb35e&acdnat=1488791936_d6e735ff465149c49bd1c20ea85f7489, DOI: 10.1016/j.ejmech.2017.02.046. [COBISS.SI-ID 4292465]

NOTO, Alessia, VITIS, Claudia De, PISANU, Maria Elena, ROSCILLI, Giuseppe, RICCI, Giulia, CATIZONE, Angiolina, SORRENTINO, Giovanni, CHIANESE, Giuseppina, TAGLIALATELA-SCAFATI, O., TRISCIUOGLIO, Daniela, DEL BUFALO, Donatella, DI MARTILE, Marta, DI NAPOLI, Arianna, RUCO, Luigi, COSTANTINI, Susan, JAKOPIN, Žiga, BUDILLON, Alfredo, MELINO, Gerry, DEL SAL, Giannino, CILIBERTO, G., MANCINI, Rita. Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ. Oncogene. 2017, vol. 36, no. 32, str. 4573-4584, tabele, ilustr. ISSN 0950-9232. http://www.nature.com/onc/journal/vaop/ncurrent/full/onc201775a.html, DOI: 10.1038/onc.2017.75. [COBISS.SI-ID 4303985]

MARKOVIČ, Tijana, JAKOPIN, Žiga, SOLLNER DOLENC, Marija, MLINARIČ-RAŠČAN, Irena. Structural features of subtype-selective EP receptor modulators. Drug discovery today. 2017, vol. 22, no. 1, str. 57-71, ilustr. ISSN 1359-6446. http://www.sciencedirect.com/science/article/pii/S1359644616302902, DOI: 10.1016/j.drudis.2016.08.003. [COBISS.SI-ID 4130929]

ŠMELCEROVIĆ, Andrija, TOMOVIĆ, Katarina, ŠMELCEROVIĆ, Žaklina, PETRONIJEVIC, Zivomir, KOCIĆ, Gordana, TOMAŠIČ, Tihomir, JAKOPIN, Žiga, ANDERLUH, Marko. Xanthine oxidase inhibitors beyond allopurinol and febuxostat : an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity. European journal of medicinal chemistry. [Print ed.]. 2017, vol. 135, str. 491-516, ilustr. ISSN 0223-5234. http://www.sciencedirect.com/science/article/pii/S0223523417302891, DOI: 10.1016/ j.ejmech.2017.04.031. [COBISS.SI-ID 4309873]

LOBELLO, Nadia, BIAMONTE, Flavia, PISANU, Maria Elena, FANIELLO, Maria Concetta, JAKOPIN, Žiga, CHIARELLA, Emanuela, GIOVANNONE, Emilia Dora, MANCINI, Rita, CILIBERTO, Gennaro, CUDA, Giovanni, COSTANZO, Francesco. Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition. Oncotarget. 2016, vol. 7, no. 38, str. 62019-62033, ilustr. ISSN 1949-2553. http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=11495, DOI: 10.18632/oncotarget.11495. [COBISS.SI-ID 4145777]

KEČEK, Kaja, URBANČIČ, Dunja, GOBEC, Martina, PEKOŠAK, Aleksandra, TOMAŠIČ, Tihomir, ANDERLUH, Marko, MLINARIČ-RAŠČAN, Irena, JAKOPIN, Žiga. Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2. Bioorganic & Medicinal Chemistry. [Print ed.]. 2016, vol. 24, iss 21, str. 5221-5234, ilustr. ISSN 0968-0896. http://www.sciencedirect.com/science/article/pii/S0968089616306526?np=y, DOI: 10.1016/j.bmc.2016.08.044. [COBISS.SI-ID 4145009]

JAKOPIN, Žiga. Orthogonally protected oxadiazole-based building blocks: synthesis and characterization. Current organic synthesis. 2016, vol. 13, no. 1, str. 126-131, ilustr. ISSN 1570-1794. http://www.eurekaselect.com/131015, http://benthamscience.com/journals/current-organic-synthesis/volume/13/issue/1/, DOI: 10.2174/1570179412666150505184852. [COBISS.SI-ID 3869809]

GOBEC, Martina, MLINARIČ-RAŠČAN, Irena, SOLLNER DOLENC, Marija, JAKOPIN, Žiga. Structural requirements of acylated Gly-l-Ala-d-Glu analogs for activation of the innate immune receptor NOD2. European journal of medicinal chemistry. [Print ed.]. 30 Jun. 2016, vol. 116, str. 1-12, ilustr. ISSN 0223-5234. http://www.sciencedirect.com/science/article/pii/S0223523416302045, DOI: 10.1016/j.ejmech.2016.03.030. [COBISS.SI-ID 4041329]

TOMAŠIČ, Tihomir, NABERGOJ, Dominik, VRBEK, Sanja, ZIDAR, Nace, JAKOPIN, Žiga, ŽULA, Aleš, HODNIK, Žiga, JUKIČ, Marko, ANDERLUH, Marko, ILAŠ, Janez, SOLLNER DOLENC, Marija, PELUSO, Jean, UBEAUD-SÉQUIER, Geneviève, MULLER, Christian D., PETERLIN-MAŠIČ, Lucija, KIKELJ, Danijel. Analogues of the marine alkaloids oroidin, clathrodin, and hymenidin induce apoptosis in human HepG2 and THP-1 cancer cells. MedChemComm. 2015, vol. 6, iss. 1, str. 105-110, ilustr. ISSN 2040-2503. http://pubs.rsc.org/en/content/articlelanding/2014/md/c4md00286e#!divAbstract, http://pubs.rsc.org/en/content/articlepdf/2015/md/c4md00286e, DOI: 10.1039/C4MD00286E. [COBISS.SI-ID 3697265]

GOBEC, Martina, TOMAŠIČ, Tihomir, MARKOVIČ, Tijana, MLINARIČ-RAŠČAN, Irena, SOLLNER DOLENC, Marija, JAKOPIN, Žiga. Antioxidant and anti-inflammatory properties of 1,2,4-oxadiazole analogs of resveratrol. Chemico-biological interactions. [Print ed.]. Oct. 2015, vol. 240, str. 200-207, ilustr. ISSN 0009-2797. http://www.sciencedirect.com/science/article/pii/S0009279715300466, DOI: 10.1016/j.cbi.2015.08.018. [COBISS.SI-ID 3914865]

JAKOPIN, Žiga. The design and synthesis of Ala-Glu/iGln mimetics : heterocyclic building blocks for pseudopeptides. Tetrahedron letters. [Print ed.]. 2015, vol. 56, issue 3, str. 504-506, ilustr. ISSN 0040-4039. http://www.sciencedirect.com/science/article/pii/S0040403914020899#, DOI: 10.1016/j.tetlet.2014.12.035. [COBISS.SI-ID 3792753]

HODNIK, Žiga, ŁOŚ, Joanna M., ŽULA, Aleš, ZIDAR, Nace, JAKOPIN, Žiga, ŁOŚ, Marcin, SOLLNER DOLENC, Marija, ILAŠ, Janez, WĘGRZYN, Grzegorz, PETERLIN-MAŠIČ, Lucija, KIKELJ, Danijel, et al. Inhibition of biofilm formation by conformationally constrained indole-based analogues of the marine alkaloid oroidin. Bioorganic & Medicinal Chemistry Letters. [Print ed.]. 2014, vol. 24, iss. 11, str. 2530-2534, ilustr. ISSN 0960-894X. http://www.sciencedirect.com/science/article/pii/S0960894X14003308#, http://ac.els-cdn.com/S0960894X14003308/1-s2.0-S0960894X14003308-main.pdf?_tid=cf3393a2-fd02-11e3-a6ec-00000aab0f02&acdnat=1403767606_1e067a1b2ef3e7dac6b690f7924993c8, DOI: 10.1016/j.bmcl.2014.03.094. [COBISS.SI-ID 3630449]

JAKOPIN, Žiga, et al. Nucleotide-binding oligomerization domain (NOD) inhibitors: a rational approach toward inhibition of NOD signaling pathway. Journal of medicinal chemistry. 2014, vol. 57, issue 16, str. 6897-6918, ilustr. ISSN 0022-2623. http://pubs.acs.org/doi/abs/10.1021/jm401841p, DOI: 10.1021/jm401841p. [COBISS.SI-ID 3630705]

ZIDAR, Nace, JAKOPIN, Žiga, MADGE, David J., CHAN, Fiona, TYTGAT, Jan, PEIGNEUR, Steve, SOLLNER DOLENC, Marija, TOMAŠIČ, Tihomir, ILAŠ, Janez, PETERLIN-MAŠIČ, Lucija, KIKELJ, Danijel, et al. Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2- aminoimidazoles as voltage-gated sodium channel modulators. European journal of medicinal chemistry. [Print ed.]. 2014, vol. 74, str. 23-30, ilustr. ISSN 0223-5234. http://www.sciencedirect.com/science/article/pii/S0223523413008222, DOI: 10.1016/j.ejmech.2013.12.034. [COBISS.SI-ID 3585905]

JAKOPIN, Žiga, et al. Murabutide revisited: a review of its pleiotropic biological effects. Current medicinal chemistry. 2013, vol. 20, no. 16, str. 2068-2079. ISSN 0929-8673. http://www.benthamscience.com/contents.php?in=108957&m=May&y=2013. [COBISS.SI-ID 3435121]

JAKOPIN, Žiga, GOBEC, Martina, KODELA, Jaka, HAZDOVAC, Toni, MLINARIČ-RAŠČAN, Irena, SOLLNER DOLENC, Marija. Synthesis of conformationally constrained $ʼgammaʼ$-D-glutamyl-meso-diaminopimelic acid derivatives as ligands of nucleotide-binding oligomerization domain protein 1 (Nod1). European journal of medicinal chemistry. [Print ed.]. Nov. 2013, vol. 69, str. 232-243. ISSN 0223-5234. http://www.sciencedirect.com/science/article/pii/S022352341300528X#, DOI: 10.1016/j.ejmech.2013.08.022. [COBISS.SI-ID 3506033]

JAKOPIN, Žiga, GOBEC, Martina, MLINARIČ-RAŠČAN, Irena, SOLLNER DOLENC, Marija. Immunomodulatory properties of novel nucleotide oligomerization domain 2 (Nod2) agonistic desmuramyldipeptides. Journal of medicinal chemistry. 2012, vol. 55, no. 14, str. 6478-6488. ISSN 0022-2623. http://pubs.acs.org/doi/pdf/10.1021/jm300503b, DOI: 10.1021/jm300503b. [COBISS.SI-ID 3274353]